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The pathology of influenza

The pathology of influenza
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Title: The pathology of influenza
Release Date: 2019-02-24
Type book: Text
Copyright Status: Public domain in the USA.
Date added: 27 March 2019
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Transcriber’s Note:

The cover image was created by the transcriber and is placed in the public domain.

PUBLISHED ON THE FOUNDATION
ESTABLISHED IN MEMORY OF
ANTHONY N. BRADY

FIG. I. AUTOPSY NO. 99. ACUTE HEMORRHAGIC AND ULCERATIVE LARYNGOTRACHEITIS.

THE
PATHOLOGY OF INFLUENZA

BY
M. C. WINTERNITZ, ISABEL M. WASON AND FRANK P. MCNAMARA
FROM
THE BRADY LABORATORY OF PATHOLOGY AND BACTERIOLOGY, YALE UNIVERSITY SCHOOL OF MEDICINE AND THE NEW HAVEN HOSPITAL
NEW HAVEN
YALE UNIVERSITY PRESS
LONDON · HUMPHREY MILFORD · OXFORD UNIVERSITY PRESS
MDCCCCXX
COPYRIGHT, 1920, BY
YALE UNIVERSITY PRESS

The present volume is the fourth work published by the Yale UniversityPress on the Anthony N. Brady Memorial Foundation, which wasestablished June 15, 1914, by members of the family of the late AnthonyN. Brady to enable the University to declare operative the agreement foran alliance between the New Haven Hospital and the Yale School ofMedicine. In addition to the pledge of endowment for this purpose, thedonors erected for the University on the grounds of the Hospital a clinicaland pathological laboratory, and have since, through additionalgifts to supplement the income of the Memorial Foundation, made possiblethe publication of this and other works by members of the facultyof the School of Medicine at Yale.

Our grateful acknowledgment is due the Staff of the New HavenHospital, especially the members of the Department of Medicine,for their hearty co-operation and for the use of the clinicalnotes. We also wish to thank the members of the Medical Corpsof the United States Army who were stationed at the Yale ArmyLaboratory School while the work was in progress and who aidedin many ways:—Colonel Charles F. Craig, Captain R. A. Lambert,Lieutenants C. A. McKinlay, Frederick Parker, Jr., EllisKellert, Henry R. Muller, and J. H. Globus.


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TABLE OF CONTENTS

        Page
 
Introduction 9
 
I. The Pathology of the Respiratory Tract in Influenza 13
 
    (A) Lesions of the Trachea and Bronchi 13
 
        (a) Gross Picture 13
        (b) Histological Picture 14
        (c) Summary 16
 
    (B) Lesions of the Lung 16
 
      (1) Acute Diffuse Fulminating Type 18
 
        (a) Gross Picture 18
        (b) Summary 19
        (c) Histological Picture 20
        (d) Summary 22
 
      (2) Localization and Necrotization of the Pneumonic Process 22
 
        (a) Gross Picture 22
        (b) Histological Picture 24
        (c) Summary 26
 
      (3) Organization of the Bronchiolar and Pneumonic Processes 26
 
        (a) Illustrative Protocols 27
        (b) Summary 30
 
II. Influence of the Respiratory Complications of Influenza upon Tuberculosis of the Lung 32
 
        (a) Illustrative Protocols 32
        (b) Summary 33
 
III. Extrarespiratory Lesions in Influenza 34
 
    (A) Lesions of the Hematopoietic System 34
 
        (a) Lymphadenoid Tissue 34
        (b) Spleen 35
        (c) Bone Marrow 35
 
    (B) Lesions of the Blood Vessels and Elsewhere in the Body 36
 
        (a) Vascular System 36
        (b) Skeletal System 36
        (c) Parenchymatous Organs 36
        (d) Alimentary Canal 37
        (e) Urinary Bladder 37
 
    (C) Miscellaneous Lesions 38
 
        (a) Parenchymatous Organs 38
        (b) Jaundice 39
        (c) Central Nervous System 39
        (d) The Pregnant Uterus 39
        (e) Summary 39
 
8IV. A Comparison between the Respiratory Lesions of Influenza and those Initiated by the Inhalation of Poisonous Gases with Special Reference to:— 40
 
    (A) The Inflammatory Response versus the Systemic Capacity to Compensate 40
 
    (B) The Primary Injury 41
 
    (C) The Tendency to Organization of Bronchiolar and Alveolar Exudates with Bronchiolitis and Bronchiolectasis as Sequelæ 42
 
   
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